文献类型： 外文期刊

作者： Qie-Gen, Liao ¹ ; Li-Juan, Yuan ¹ ; Jian-Jun, Xiang ¹ ; Da-Wen, Zhang ¹ ; Lin-Guang, Luo ¹ ;

作者机构： 1.Jiangxi Acad Agr Sci, State Key Lab Qual & Safety Agroprod Jiangxi Prov, Inst Qual Safety Stand Agr Prod Res, Nanchang 330200, Jiangxi, Peoples R China

关键词： CO2 effervescence-assisted emulsification microextraction; Switchable fatty acid; Azaperone; Swine adipose samples

期刊名称：FOOD ANALYTICAL METHODS （ 影响因子：3.366； 五年影响因子：3.07 ）

ISSN： 1936-9751

年卷期：

页码：

收录情况： SCI

摘要： In this work, CO2 effervescence-assisted emulsification microextraction method using an efficient switchable solvent was proposed for the enrichment of azaperone and azaperol in swine adipose samples. The azaperone and azaperol in swine adipose were extracted by 1% (v/v) ammoniated acetonitrile at 55 degrees C. A medium-chain fatty acid as switchable-hydrophilicity solvent is used for further enrichment and purification, and it is able to be easily switched into hydrophobic/hydrophilic forms in pH changeable media. The main parameters were optimized as follows: 100 mg octanoic acid, 0.3 mL acetic acid-water solution (1:1, v/v), and 0.5 mL 3.0 mol L-1 Na2CO3 solution. Under the optimal conditions, azaperone and azaperol showed good linearity within the studied range, and the values of the correlation coefficient were higher than 0.999. The limits of detection for the method ranged from 5 to 10.0 ng kg(-1). The recoveries of azaperone and azaperol in swine adipose were 95-104%, with relative standard deviations ranging from 3 to 5%. The proposed method was successfully applied for the analysis of azaperone and azaperol in swine adipose samples.