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Sensitive Electrochemical Immunosensor for Procymidone Detection Based on a Supramolecular Amplification Strategy

文献类型： 外文期刊

作者： Ai, Qiushuang 1 ; Yu, Xiren 1 ; Dong, Yifan 1 ; Zhang, Li 1 ; Liang, Jingtian 1 ; Zhang, Dawen 1 ; Qiu, Suyan 1 ;

作者机构： 1.Jiangxi Acad Agr Sci, Inst Qual & Safety & Stand Agr Prod Res, Key Lab Qual & Safety Control Poultry Prod, Minist Agr & Rural Affairs Peoples Republ China, Nanchang 330200, Jiangxi, Peoples R China

期刊名称：ACS OMEGA （ 影响因子：4.3； 五年影响因子：4.4 ）

ISSN： 2470-1343

年卷期： 2025 年 10 卷 3 期

页码：

收录情况： SCI

摘要： A sensitive electrochemical immunosensor for procymidone detection was developed based on a supramolecular amplification strategy. beta-Cyclodextrin (beta-CD)-based nanomaterials were employed to immobilize ferrocene derivative (FC)-functionalized antibodies/antigens through host-guest interactions. With the presence of procymidone, the formed beta-CD-labeled bioconjugates were immobilized on the antibody-modified electrode after the immunoreaction, indicating fabrication of the immunosensor. The FC/beta-CD complexes were with multiplex electroactive species and provided more sites for recognition groups, resulting in signal amplification of the sensor. Monitored with differential pulse voltammetry, the proposed immunosensor exhibited a wide linear range from 5 pM to 0.1 mu M with a low detection limit (LOD) of 1.67 pM. The as-prepared immunosensor possessed high sensitivity, specificity, and stability and showed great potential for monitoring procymidone in the field of food safety.

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