文献类型： 外文期刊

作者： Tan, M. -F. ¹ ; Tan, J. ¹ ; Zeng, Y. -B. ¹ ; Li, H. -Q. ¹ ; Yang, Q. ¹ ; Zhou, R. ² ;

作者机构： 1.Jiangxi Acad Agr Sci, Inst Anim Husb & Vet Sci, Nanchang 330200, Jiangxi, Peoples R China

2.Huazhong Agr Univ, Coll Vet Med, State Key Lab Agr Microbiol, Wuhan, Peoples R China

3.Cooperat Innovat Ctr Sustainable Pig Prod, Wuhan, Peoples R China

4.Minist Sci & Technol China, Int Res Ctr Anim Dis, Wuhan, Peoples R China

关键词： antimicrobial resistance; China; clinically healthy pigs; genotype; integrative and conjugative elements; multidrug resistance; Streptococcus suis

期刊名称：JOURNAL OF APPLIED MICROBIOLOGY （ 影响因子：3.772； 五年影响因子：3.963 ）

ISSN： 1364-5072

年卷期：

页码：

收录情况： SCI

摘要： Aims This study aimed to investigate the antimicrobial resistance (AMR) profiles and genotypes ofStreptococcus suisfrom Jiangxi Province, China. Methods and Results A total of 314 nasal swab samples were collected from clinically healthy pigs, with a positive isolation rate ofS. suisof 34 center dot 08%. Antimicrobial susceptibility testing showed that more than 80% of the isolates were susceptible to vancomycin, penicillin, minocycline and chloramphenicol. A high frequency of resistance to clindamycin, tetracycline, clarithromycin and erythromycin was observed. All of the isolates were resistant to three or more categories of antimicrobials. Theerm(B) andtet(O) served as the most frequent genotypes that contributed to lincosamide, macrolide and tetracycline resistances. A part of macrolide-resistant genotypes could not exhibit specific phenotypes. Finally, integrative and conjugative elements (ICEs) were identified in 28 center dot 97% of the isolates. Conclusions The multidrug resistance ofS. suishas widely emerged in Jiangxi Province. The most prevalent resistance genes and genotypes were similar to those in other regions or countries. The presence of ICEs is increasing the risk of horizontal transfer of AMR genes. Significance and Impact of the Study The findings could provide guidance for the rational use of antimicrobial drugs and be helpful for monitoring the AMR information ofS. suisin China.