Nuclease treatment enhanced the ameliorative effect of yeast culture on epidermal mucus, hepatic lipid metabolism, inflammation response and gut microbiota in high-fat diet-fed zebrafish
文献类型： 外文期刊
作者： Zhao, Yajie 1 ; Hao, Qiang 2 ; Zhang, Qingshuang 2 ; Yang, Yalin 4 ; Ran, Chao 4 ; Xu, Qiyou 1 ; Wu, Chenglong 1 ; Liu, Wenshu 5 ; Li, Siming 5 ; Zhang, Zhen 4 ; Zhou, Zhigang 1 ;
作者机构： 1.Huzhou Univ, Coll Life Sci, Huzhou, Peoples R China
2.Chinese Acad Agr Sci, Feed Res Inst, China Norway Joint Lab Fish Gut Microbiota, Beijing, Peoples R China
3.Norwegian Univ Sci & Technol, Inst Biol, Norway China Joint Lab Fish Gut Microbiota, N-7491 Trondheim, Norway
4.Chinese Acad Agr Sci, Feed Res Inst, Key Lab Feed Biotechnol Minist Agr & Rural Affairs, Beijing 100081, Peoples R China
5.Jiangxi Acad Agr Sci, Inst Anim Husb & Vet, Nanchang 330200, Jiangxi, Peoples R China
6.Chinese Acad Agr Sci, Inst Feed Res, Sino Norway Joint Lab Fish Gut Microbiota, Beijing 100081, Peoples R China
关键词： Yeast culture; Nuclease; Lipid metabolism; Inflammation response; Gut microbiota; High-fat diet
期刊名称：FISH & SHELLFISH IMMUNOLOGY （ 影响因子：4.622； 五年影响因子：4.799 ）
ISSN： 1050-4648
年卷期： 2022 年 131 卷
页码：
收录情况： SCI
摘要： As a functional feed additive, yeast cultures are rich in nucleotides, and adding extra nuclease can significantly increase the content of nucleotides in yeast culture. In this experiment, the effects on growth, epidermal mucus, liver and intestinal health of zebrafish were evaluated by supplementing the yeast culture or nuclease-treated yeast culture with a high-fat diet (HFD). One-month-old zebrafish were fed four diets: normal diet (NORM), HFD, yeast culture diet (YC), and nuclease-treated yeast culture diet (YC (N)) for three weeks. Results showed that the complement 4 activity of the epidermal mucus in YC (N) group was significantly higher than those in HFD and YC groups (P < 0.05). The YC and YC (N) significantly reduced the content of hepatic triglyceride caused by HFD (P < 0.05). Moreover, compared with the YC group, the YC (N) significantly increased the expression of lipolysis genes, such as PPAR alpha, PGC1 alpha, ACOX3 (P < 0.05). Compared with the YC group, the YC (N) group significantly increased the expression of liver pro-inflammatory factors TNF alpha, IL-6, IL-1 beta and anti-inflammatory factors TGF beta, IL-10 (P < 0.05). The diet YC and YC (N) significantly improved the height of the intestinal villus (P < 0.05). Compared with the HFD group, the YC (N) group significantly increased the expression of intestinal pro-inflammatory factors TNF alpha, IL-6 and anti-inflammatory factors TGF beta, IL-10 (P < 0.05). The YC (N) group significantly decreased the abundance of intestinal Proteobacteria and Acinetobacter, and increased the abundance of intestinal Actinobacteria, Mycobacterium and Rhodobacter (P < 0.05). In conclusion, compared with the supplement of yeast culture, nuclease treated yeast culture can further alleviate the adverse effects of HFD on liver and intestinal health, and be used as feed additives for the nutritional and immune regulation of fish.
- 相关文献
作者其他论文 更多>>
-
The direct and gut microbiota-mediated effects of dietary bile acids on the improvement of gut barriers in largemouth bass (Micropterus salmoides)
作者：Xia, Rui;Zhang, Qingshuang;Xia, Dongmei;Hao, Qiang;Ding, Qianwen;Zhou, Zhigang;Hao, Qiang;Ding, Qianwen;Ran, Chao;Yang, Yalin;Zhang, Zhen;Cao, Aizhi;Zhou, Zhigang
关键词：Bile acids; Gut barrier; Gut microbiota; Largemouth bass; Germ -free zebra fish
-
Effects of dietary lentinan on growth performance, nonspecific immunity and disease resistance to Aeromonas hydrophila in largemouth bass (Micropterus salmoides)
作者：Wang, Yuzhu;Liu, Wenshu;Tang, Yanqiang;Xiao, Haihong;Guo, Xiaoze;Li, Siming;Li, Xiaoyong;Xin, Yuxiu
关键词：Lentinan; Largemouth bass; Growth; Immunity; Disease resistance
-
Effects of dietary oxidized fish oil on the growth performance, intestinal health, and antioxidant capacity of zebrafish
作者：Jiang, Weiwei;Wu, Yancheng;Li, Debing;Guo, Xiaoze;Liu, Wenshu;Wang, Yuzhu;Li, Siming
关键词：antioxidant; growth performance; intestinal health; oxidized fish oil
-
A compound of paraprobiotic and postbiotic derived from autochthonous microorganisms improved growth performance, epidermal mucus, liver and gut health and gut microbiota of common carp (Cyprinus carpio)
作者：Meng, Delong;Hao, Qiang;Zhang, Qingshuang;Yu, Zhe;Liu, Shubin;Zhou, Zhigang;Hao, Qiang;Yang, Yalin;Ran, Chao;Zhang, Zhen;Zhou, Zhigang
关键词：Paraprobiotic; Postbiotic; Common carp; Gut microbiota; Liver
-
Addition of solid-state fermentation product of yeast ameliorated the effects of high-fat diet on hepatic lipid metabolism, epidermal mucus, intestine and liver health, and gut microbiota of zebrafish
作者：Li, Jie;Xia, Dongmei;Hao, Qiang;Zhang, Qingshuang;Zhou, Zhigang;Jing, Xiufang;Zhao, Yajie;Xu, Qiyou;Wu, Chenglong;Hao, Qiang;Xie, Mingxu;Yang, Yalin;Zhang, Zhen;Zhou, Zhigang;Wu, Chenglong;Zhou, Zhigang
关键词：Solid-state fermentation product; Saccharomyces cerevisiae; High-fat diet; Lipid metabolism; Inflammation response; Gut microbiota
-
Effects of choline chloride on intestinal microbiota and its association with liver fat accumulation in zebrafish
作者：Liu, Wenshu;Guo, Xiaoze;Chen, Yanliang;Tang, Yanqiang;Xiao, Haihong;Wang, Yuzhu;Li, Siming;Zhou, Zhigang;Liu, Wenshu;Zhou, Zhigang
关键词：Choline chloride; Liver fat; Gut bacteria; Fish
-
Partially replacing dietary fish meal by Saccharomyces cerevisiae culture improve growth performance, immunity, disease resistance, composition and function of intestinal microbiota in channel catfish (Ictalurus punctatus)
作者：Hao, Qiang;Xia, Rui;Zhang, Qingshuang;Xie, Yadong;Zhou, Zhigang;Hao, Qiang;Ran, Chao;Yang, Yalin;Zhang, Zhen;Zhou, Wenhao;Chu, Fuwei;Zhang, Xiaomei;Wang, Yu;Zhou, Zhigang
关键词：Saccharomyces cerevi siae culture; Channel catfish; Intestinal microbiota; Germ free zebrafish model
