文献类型： 外文期刊

作者： Duan, Yifan ¹ ; Yan, Jiping ¹ ; Zhu, Yue ¹ ; Zhang, Cheng ¹ ; Tao, Xiuhua ³ ; Ji, Hongli ³ ; Zhang, Min ¹ ; Wang, Xianrong ¹ ; Wang, Long ⁴ ;

作者机构： 1.Nanjing Forestry Univ, Coll Biol & Environm, Coinnovat Ctr Sustainable Forestry Southern China, Key Lab State Forestry & Grassland Adm Subtrop Fo, 159 Longpan Rd, Nanjing 210037, Peoples R China

2.Nanjing Forestry Univ, Int Cultivar Registrat Ctr Osmanthus, 159 Longpan Rd, Nanjing 210037, Peoples R China

3.Jiangxi Acad Agr Sci, Vegetable & Flowers Res Inst, 1738 Liantang Middle Blvd, Nanchang 330200, Jiangxi, Peoples R China

4.Nanjing Univ, Sch Life Sci, State Key Lab Pharmaceut Biotechnol, 163 Xianlin Ave, Nanjing 210023, Peoples R China

关键词： ageing; clonal variation; Osmanthus fragrans; somatic mutation; tree evolution

期刊名称：TREE PHYSIOLOGY （ 影响因子：4.561； 五年影响因子：5.121 ）

ISSN： 0829-318X

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收录情况： SCI

摘要： Lifespan varies greatly between and within species. Mutation accumulation is considered an important factor explaining this life-history trait. However, direct assessment of somatic mutations in long-lived species is still rare. In this study, we sequenced a 1700-year-old sweet olive tree and analysed the high-frequency somatic mutations accumulated in its six primary branches. We found the lowest per-year mutation accumulation rate in this oldest tree among those studied via the whole-genome sequencing approach. Investigation of mutation profiles suggests that this low rate of high-frequency mutation was unlikely to result from strong purifying selection. More intriguingly, on a per-branching scale, the high-frequency mutation accumulation rate was similar among the long-lived individuals such as oak, wild peach and sweet olive investigated here. We therefore suggest the possibility that the accumulation of high-frequency somatic mutations in very long-lived trees might have an upper boundary due to both the possible limited number of stem cell divisions and the early segregation of the stem cell lineage.