文献类型: 外文期刊
作者: Qiu, Suyan 1 ; Zhao, Fusheng 2 ; Li, Jingting 2 ; Shih, Wei-Chuan 2 ;
作者机构: 1.Jiangxi Acad Agr Sci, Inst Qual & Safety & Stand Agr Prod Res, Nanchang 330200, Jiangxi, Peoples R China
2.Univ Houston, Dept Elect & Comp Engn, 4800 Calhoun Rd, Houston, TX 77004 USA
3.Univ Houston, Dept Chem, 4800 Calhoun Rd, Houston, TX 77004 USA
4.Univ Houston, Dept Chem Engn, 4800 Calhoun Rd, Houston, TX 77004 USA
5.Univ Houston, Program Mat Sci & Engn, 4800 Calhoun Rd, Houston, TX 77004 USA
关键词: Portable SERS;Nanoporous gold nanoparticle;NPG-NP array chip;Guanine-quadruplex;Malachite green
期刊名称:OPTICAL DIAGNOSTICS AND SENSING XVII: TOWARD POINT-OF-CARE DIAGNOSTICS
ISSN: 0277-786X
年卷期: 2017 年 10072 卷
页码:
收录情况: SCI
摘要: Sensitive detection of specific chemicals on site can be extremely powerful in many fields. Owing to its molecular fingerprinting capability, surface-enhanced Raman scattering has been one of the technological contenders. In this paper, we describe the novel use of DNA topological nanostructure on nanoporous gold nanoparticle (NPG-NP) array chip for chemical sensing. NPG-NP features large surface area and high-density plasmonic field enhancement known as "hotspots". Hence, NPG-NP array chip has found many applications in nanoplasmonic sensor development. This technique can provide novel label-free molecular sensing capability and enables high sensitivity and specificity detection using a portable Raman spectrometer.
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